Evansville is a city in Vanderburgh County, Indiana, United States, and its county seat. With a population of 118,414 at the 2020 census, it is the third-most populous city in Indiana, the most populous city in Southern Indiana, and the 249th-most populous city in the United States. It is the central city of the Evansville metropolitan area, a hub of commercial, medical, and cultural activity of s…